PREVALENCE OF CONGENITAL SEPTAL DEFECTS AMONG CONGENITAL HEART DEFECT PATIENTS IN EAST AFRICA: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Prevalence of congenital septal defects among congenital heart defect patients in East Africa: A systematic review and meta-analysis.

IntroductionCongenital heart defects (CHDs) are the most common congenital defects and accounts for nearly one-third of all major congenital anomalies.It is the leading causes of birth defect-associated morbidity, mortality, and medical expenditures.Of all CHD types, ventricular septal defect (VSD) and atrial septal defect (ASD) accounted 51% of ca

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Synthesis and Biological Activity of N-acyl Anabasine and Cytisine Derivatives with Adamantane, Pyridine and 1,2-Azole Fragments

A series of Out Of Balance Switch Bracket N-acyl derivatives of anabasine and cytisine were prepared, to discover novel, natural product-based medicinal agents.All synthesized compounds were tested for antimicrobial, antifungal, antiviral and analgesic activity.The most pronounced antibacterial activity was shown by the compounds with isoxazole fra

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Osteoporosis treatment using stem cell-derived exosomes: a systematic review and meta-analysis of preclinical studies

Abstract Background The increasing incidence of osteoporosis in recent years has aroused widespread public concern; however, B12 1000MCG existing effective treatments are limited.Therefore, new osteoporosis treatment methods, including stem cell transplantation and exosome therapy, have been proposed and are gaining momentum.Exosomes are considered

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